Princess Beatrice and her husband Edoardo Mapelli Mozzi were seen leaving Clarence House in central London on Tuesday morning just hours after the King’s cancer diagnosis was announced.

The pair were seen departing Charles’ residence after an apparent visit but appeared to be smiling from behind the wheel of their vehicle.

It was announced on Monday evening that while in hospital for an operation on his prostate, medics spotted a second issue ‘of concern’ for the monarch, which has since been confirmed to be cancerous. 

It is the second blow for Princess Beatrice after her mother, Sarah Ferguson, was recently diagnosed with a form of skin cancer. 

The King spent last night at home in London after beginning out-patient cancer treatment – as family and friends revealed that the monarch remains ‘hugely positive’ following his bombshell diagnosis. 

Princess Beatrice and her husband Edoardo Mapelli Mozzi are seen leaving Clarence House on Tuesday morning

Princess Beatrice and her husband Edoardo Mapelli Mozzi are seen leaving Clarence House on Tuesday morning

King Charles has been diagnosed with cancer , Buckingham Palace announced in a statement. Above: Charles was last seen waving to well-wishers as he attended a service with his wife Queen Camilla at St Mary Magdalene Church in Sandringham, Norfolk, on Sunday

King Charles has been diagnosed with cancer , Buckingham Palace announced in a statement. Above: Charles was last seen waving to well-wishers as he attended a service with his wife Queen Camilla at St Mary Magdalene Church in Sandringham, Norfolk, on Sunday

Buckingham Palace said in a statement last night: ‘During The King’s recent hospital procedure for benign prostate enlargement, a separate issue of concern was noted. Subsequent diagnostic tests have identified a form of cancer.

‘His Majesty has today commenced a schedule of regular treatments, during which time he has been advised by doctors to postpone public-facing duties. Throughout this period, His Majesty will continue to undertake State business and official paperwork as usual.

‘The King is grateful to his medical team for their swift intervention, which was made possible thanks to his recent hospital procedure. He remains wholly positive about his treatment and looks forward to returning to full public duty as soon as possible.

‘His Majesty has chosen to share his diagnosis to prevent speculation and in the hope it may assist public understanding for all those around the world who are affected by cancer.’

For Beatrice and her sister Eugenie, it is the latest in a series of family health blows which has most recently seen their mother, Sarah Ferguson, struck down with her second cancer diagnosis in a year. 

In a similar process to the King, it was during reconstructive surgery that the duchess had a series of moles removed for analysis, one of which was found to be cancerous.

She told royal fans the second diagnosis was a ‘shock’ but that she remained in ‘good spirits’ as she praised doctors for identifying the issue early. 

It was last month announced the Duchess has been diagnosed with malignant melanoma – just months after undergoing a second bout of reconstructive surgery following her breast cancer diagnosis.

Princess Beatrice was spotted behind the wheel of the couple's car after a visit to the King's residence

Princess Beatrice was spotted behind the wheel of the couple’s car after a visit to the King’s residence

Princess Beatrice was seen visiting Clarence House on Tuesday morning (file image)

Princess Beatrice was seen visiting Clarence House on Tuesday morning (file image)

It comes just weeks after Princess Beatrice's mother, Sarah Ferguson, was diagnosed with a form of skin cancer

It comes just weeks after Princess Beatrice’s mother, Sarah Ferguson, was diagnosed with a form of skin cancer

When he was discharged from hospital last Monday, the King appeared steady on his feet as he walked out of the London Clinic in Marylebone with Queen Camilla by his side

When he was discharged from hospital last Monday, the King appeared steady on his feet as he walked out of the London Clinic in Marylebone with Queen Camilla by his side

Buckingham Palace said in a statement on Monday: 'During The King's recent hospital procedure for benign prostate enlargement, a separate issue of concern was noted. Subsequent diagnostic tests have identified a form of cancer'

Buckingham Palace said in a statement on Monday: ‘During The King’s recent hospital procedure for benign prostate enlargement, a separate issue of concern was noted. Subsequent diagnostic tests have identified a form of cancer’

At the time of her diagnosis, the Duchess posted on Instagram: ‘I have been taking some time to myself as I have been diagnosed with malignant melanoma, a form of skin cancer, my second cancer diagnosis within a year after I was diagnosed with breast cancer this summer and underwent a mastectomy and reconstructive surgery.

‘It was thanks to the great vigilance of my dermatologist that the melanoma was detected when it was.

‘Naturally another cancer diagnosis has been a shock but I’m in good spirits and grateful for the many messages of love and support.

‘I believe my experience underlines the importance of checking the size, shape, colour and texture and emergence of new moles that can be a sign of melanoma and urge anyone who is reading this to be diligent.

‘I am incredibly thankful to the medical teams that have supported me through both of these experiences with cancer and to the MAYRLIFE Clinic for taking gentle care of me in the past weeks, allowing me time for recuperation. I am resting with family at home now, feeling blessed to have their love and support.’

It is now Princess Beatrice’s uncle who has suffered the latest family health blow.

King Charles is said to have personally informed his close relatives of his diagnosis, which is not prostate cancer, including his two sons the Prince of Wales and the Duke of Sussex.

Prince Harry is understood to be rushing to return to the UK today to see his father, with a potential rapprochement with brother Prince William on the cards.

A source close to Harry said that he had immediately decided to come to the UK to be by his father’s side. Experts have claimed that Harry’s dash to Britain ‘indicates the seriousness’ of the King’s condition.

Announcing that Prince Harry will come and see his father, the Office of The Duke and Duchess of Sussex said: ‘The duke did speak with his father about his diagnosis. He will be traveling to UK to see His Majesty in the coming days.’

After his diagnosis was revealed the King spent his first night at home after beginning outpatient treatment. It is understood his prognosis is good and that the cancer was caught early. 

Family and friends were said to be amazed by the King’s determination to carry on with ‘business as usual’. 

A family friend said: ‘He and his doctors are very, very positive.’ 

Queen Camilla will be at her husband’s side throughout but has insisted on continuing with her public engagements. 

Other members of the Royal Family will be stepping up to stand in for the sovereign, including the Prince of Wales, who will return to duties tomorrow after his own wife’s medical issues. 

The Princess of Wales was herself admitted to the same hospital, The London Clinic, in recent weeks for planned abdominal surgery.

She is expected to be out of action until at least after Easter, requiring up to three months to recover.

With so many senior royals suffering health scares, other members of the family including Prince William and Princess Anne are expected to pick up the slack. 

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